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Ambien (Zolpidem) is a prescription sedative-hypnotic used for short-term treatment of insomnia. It works by slowing brain activity to help you fall asleep faster and stay asleep longer, with most users falling asleep within 30 minutes. Available in 5mg, 10mg, and Ambien CR 6.25mg and 12.5mg extended-release strengths. As a Schedule IV controlled substance, ...